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Abstract #2605

Quantification of multiple organ iron deposition in transfusion dependent diseases using mDIXON-Quant technique

Qiaoling Wu1, Zhizheng Zhuo2, and Hongyan Ni3

1Tianjin University of Traditional Chinese Medicine, Tianjin, China, 2Clincial Science, Philips Healthcare, Beijing, China, 3Tianjin First Center Hospital, Tianjin, China

Iron overload is a common complication of transfusion dependent patients. Magnetic resonance imaging can be used for quantitative detection of iron deposition in transfusion dependent patients. A total intake of iron for transfusion was evaluated based on the mDIXON-Quant and 3D-FFE sequence respectively. Because the mdixon-quant can avoid the effect of fat on the iron overload evaluation, the mDIXON-Quant sequence can more accurately quantify iron deposition in liver and pancreas than 3D-FFE sequence. The quantitative application of mDIXON-Quant in detection of iron deposition in patients can provide reliable basis for iron chelation therapy in clinic.

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