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Abstract #2640

Renal Relaxivity Mapping at 3.0 T for the Diagnosis of Chronic Kidney Disease – Initial Experience

Muditha S Bandara1, Chirath Sulalith2, Narayana Rolla3, Indrajit Saha4, Aruna Pallewatte2, and Janaka P Wansapura1

1Department of Physics, University of Colombo, Colombo 03, Sri Lanka, 2Department of Radiology and Neuroradiology, National Hospital of Sri Lanka, Colombo, Sri Lanka, 3Philips Health Systems, Philips India Ltd, Bangalore, Karnataka, India, 4Philips Health Systems, Philips India Ltd, Gurgaon, Haryana, India

Detection of early stage Chronic Kidney Disease (CKD) is essential to improve patient outcome but remains a challenge. In this study we generated T1 and T2 maps of renal cortex at 3.0 T in CKD patients and healthy volunteers (n=16). Modified Look-Locker sequence with simulated ECG and a multi-echo Gradient and Spin-Echo sequence were used to generate T1 and T2 maps respectively. T1 of CKD kidney (1752 ± 45 ms) was significantly higher (P < 0.001) than that of healthy kidney (1538 ± 37 ms). There was no significant difference between the groups in T2, FWHM and skewness of T2.

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