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Abstract #2668

Rapid dynamic contrast-enhanced MRI for small animals at 7T using 3D UTE-GRASP

Jin Zhang1, Li Feng1, Ricardo Otazo1, and Sungheon Gene Kim1

1Center for Biomedical Imaging (CBI), Center for Advanced Imaging Innovation and Research (CAI2R), New York University School of Medicine, New York, NY, United States

It remains challenging to achieve simultaneous high spatial isotropic resolution and high temporal resolution in dynamic contrast enhanced (DCE) MRI of small animals, due to the relatively low signal to noise ratio (SNR) from small voxels. The purpose of this study is to develop a highly accelerated, high-spatial and high-temporal resolution DCE-MRI method for small animal imaging at 7T using 3D ultrashort echo time (UTE) golden-angle radial sampling with a combined compressed sensing and parallel imaging approach based on the GRASP technique. Our preliminary results demonstrate that the proposed UTE-GRASP method has the potential to improve both spatial and temporal resolution.

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