Abstract #2878

Short-term Fourier Transform Analysis of Respiratory- and Cardiac-driven Pulsation of Cerebrospinal Fluid under Free Breathing

Tetsuya Tokushima¹, Satoshi Yatsushiro², Saeko Sunohara¹, Mitsunori Matsumae³, Hideki Atsumi³, and Kagayaki Kuroda^1,2

¹Cource of Electrical and Electric Engineering, Guraduate School of Engineering, Tokai University, Hiratsuka, Kanagawa, Japan, ²Guraduate School of Information Science and Technology, Tokai University, Hiratsuka, Kanagawa, Japan, ³Department of Neurosurgery, Tokai University, Isehara, Kanagawa, Japan

To separate the respiratory- and cardiac-driven motions of cerebrospinal fluid (CSF) under free breathing, CSF velocity in 7 healthy volunteers and 3 hydrocephalus patients were observed by asynchronous phase contrast (PC) technique with monitoring respiratory and ECG signals. Spectrograms of CSF velocity and respiratory signal obtained by short-term Fourier transform (STFT) with 8-sec length Hamming window revealed that the peak respiratory motion appeared in 0-0.5 Hz band, while the cardiac motion appeared around 1-1.5 Hz. These results suggest that the separation of the two motion components is possible by sliding the frequency bands temporarily according to the spectrogram.

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