Extravascular fluid transport have been reported both in human and animal studies during recent decades. Our previous work demonstrated a long-distance extravascular fluid transport which is consisted of oriented fibrous connective tissues in venous adventitia, arterial adventitia and dermis of amputated lower extremities. To further explore the pattern of fluid transport along lower extremity arteries, we implemented contrast enhanced MRI in volunteers and tracked the longitudinal contrast agent transportation. The periarterial regions near tibia showed high signal intensity after contrast agent administration suggest an unexplored extravascular fluid transport. This study may provide a novel diagnosis method of PAD.