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Abstract #3088

Brain White Matter Microstructure Changes in Alzheimer disease with Type 2 diabetes:a DKI study

Junyi Dong1, Liang Han1, Xiaoxin Li1, and Yanwei Miao1

1Department of Radiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China

In this study, the groups were respectively used as the people with Alzheimer disease with type 2 diabetes, Alzheimer disease without type 2 diabetes and healthy person, the effect of high blood glucose on the microstructure in patients with type 2 diabetes mellitus, and the changes on microstructure in patients with AD patients were studied used DKI study, and it was concluded that the high blood glucose level may have certain damage to the microstructure of the white matter. In conclusion, DKI study can evaluate secondary brain microstructure changes from hyperglycemia in T2DM patients.

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