1Cedars-Sinai Medical Center, Los Angeles, CA, United States, 2University of California, Los Angeles, CA, United States, 3Xuanwu Hospital, Beijing, China, 4Guangzhou Medical University, Guangzhou, China, 5Siemens Healthineers, Los Angeles, CA, United States
Atherosclerotic disease of the aortic arch has been considered a potential cause of cryptogenic stroke. Vessel wall MR imaging can directly probe atherosclerotic lesions to provide assessment of plaque burden and instability. However, its clinical adoption for the aortic arch is hindered primarily by long imaging time that is associated with the needs for large spatial coverage, high spatial resolution, compensation of motion, and multiple image contrasts. In this work, we proposed a fast 3D dual-contrast vessel wall MR technique that is potentially useful for detecting intraplaque hemorrhage and calcification as well as measuring plaque burden at the aortic arch.
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