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Abstract #3567

Susceptibility-Induced Distortion Correction in Hyperpolarized Echo Planar Imaging

Jack J J J Miller1,2,3, Angus Z Lau1,4, and Damian J Tyler1,3

1Oxford Centre for Clinical Magnetic Resonance Research, University of Oxford, Oxford, United Kingdom, 2Department of Physics, University of Oxford, Oxford, United Kingdom, 3Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom, 4Sunnybrook Research Institute, Toronto, ON, Canada

Echo Planar Imaging is an attractive rapid imaging readout that can image hyperpolarized compounds in vivo. By alternating the sign of the phase encoding gradient waveform, spatial offsets arising from uncertain frequency shifts can be determined. We show here that blip-reversed EPI can also be used to correct for susceptibility and $$$B_0$$$ inhomogeneity effects that would otherwise produce image-domain distortion in the heart, through the use of an estimated deformation field that is calculated from the acquired data.

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