Abstract #3659

Epileptogenesis Imaging biomarker identification in the Mesial Temporal lobe epilepsy (MTLE) mouse model

Yvan Dietrich¹, Gabriel Dieuset¹, Mélanie Lagarrigue², Hervé Saint-Jalmes¹, Benoit Martin¹, Charles Pineau², Fabrice Wendling¹, and Pierre-Antoine Eliat³

¹Laboratoire du Traitement du Signal et de l’Image (LTSI) - Inserm UMR 1099, Université de Rennes 1, Rennes, France, ²Protim Core Facility Biogenouest, IRSET - Inserm UMR 1085, Université de Rennes 1, Rennes, France, ³PRISM - Biosit CNRS UMS 3480, INSERM UMS 018, Université de Rennes 1, Rennes, France

This work presents preliminary promising results on Mesial temporal lobe epilepsy (MTLE) mouse model suggesting that MRI/MRS-based biomarkers could be of great interest to detect early changes in the lesioned brain and to characterize epileptogenesis after traumatic brain injury.

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