Abstract #3670

Time makes the difference: Comparison of ADC values obtained with OGSE and PGSE sequences for differentiation of human head and neck tumors

Mami Iima^1,2, Akira Yamamoto¹, Ichiro Tateya³, Morimasa Kitamura³, Thorsten Feiweier⁴, Koichi Omori³, and Kaori Togashi¹

¹Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan, ²Hakubi Center for Advanced Research, Kyoto University, Kyoto, Japan, ³Department of Otolaryngology, Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan, ⁴Siemens Healthcare GmbH, Erlangen, Germany

The correlation of ADC values with different diffusion times, as obtained from OGSE and PGSE, was investigated in patients with head and neck tumors. A significant decrease of ADC values in head and neck cancers was noted with the increase of diffusion time (p < .0.05). Care needs to be taken when interpreting OGSE-ADC and PGSE-ADC values, as flow effects will contribute to these values, which was suspected in light of the (artefactual) increase of ADC values using PGSE compared to OGSE.

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