Gastric cancer (GC) is the second most common cause of cancer-related mortality globally. Histological assessment of GC has been based on Lauren classification which categorizes the tumor according to its morphological features. In respond to the need for probing biological tissue complexity, a growing number of diffusion-weighted imaging studies have focused on revealing tissue microstructures by measuring non-Gaussian diffusion behaviors. One of these techniques is the fractional order calculus (FROC) model. In this study, we have used the FROC model to investigate non-invasive imaging-based assessment of GC, providing an alternative to histopathology-based Lauren classification.
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