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Abstract #3846

High Resolution Semi-LASER Localized Echo Planar Spectroscopic Imaging at Ultra High Field

Eduardo Coello1,2, Ralph Noeske3, Brian L. Burns4, Jeremy W. Gordon5, Angela Jakary5, Bjoern Menze1, Axel Haase1, Peder E.Z. Larson5, Yan Li5, and Rolf F. Schulte2

1Technische Universit√§t M√ľnchen, Munich, Germany, 2GE Healthcare, Munich, Germany, 3MR Applied Science Lab Europe, GE Healthcare, Berlin, Germany, 4MR Applied Science Lab, GE Healthcare, Menlo Park, CA, United States, 5Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, United States

This work presents a robust framework for fast high-resolution 1H MRSI at 7 Tesla using semi-localized by adiabatic selective refocusing (semi-LASER) and high-bandwidth symmetric echo planar spectroscopic imaging (EPSI). Inconsistencies in the symmetric EPSI trajectory are corrected using a single shot water reference scan, effectively removing spectral ghosting. With the proposed methodology, high-resolution metabolite ratio maps that show correlation with anatomical structures were obtained under 5-minutes.

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