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Abstract #4057

Assessment of Iron Oxide Nanoparticle Concentration for Distinct Intercranial EEG Electrode Localization in MRI

Johannes B. Erhardt1,2, Jessica A. Martinez2, Tyler E Cork2, Isabel Gessner3, Sanjay Mathur3, Thomas Stieglitz1, and Daniel B. Ennis2

1University of Freiburg, Freiburg, Germany, 2UCLA, Los Angeles, CA, United States, 3University of Cologne, Cologne, Germany

IcEEG electrodes for epilepsy and research applications impair fMRI and MR images with compromising susceptibility artifacts. Thin-film implants feature 100x less metal thickness and thus minimal artifacts. However, thin-film implants are inconspicuous in MRI. Therefore we present means of localization using super paramagnetic iron oxide nano particles to make thin-film implants ready for future applications. We present feasible concentrations and proof of concept.

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