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Abstract #4088

A Comparison of Prospective versus Retrospective Motion Correction for Reliable T1-Weighted Neuroimaging

Steven Kecskemeti1, Abigail Freeman1, and Andrew Alexander1

1University of Wisconsin - Madison, Madison, WI, United States

Prospective motion corrected MPRAGE T1-weighted images were compared against retrospectively motion corrected MPnRAGE T1-weighted images. 14 young children were scanned without sedation and without the head being stabilized with pads. Dice-overlap of automatic tissue segementation masks (FAST and FLIRT) were used as a measure of reliability. MPnRAGE with motion correction showed exceptional regional label consistency (>=80% Dice overlaps for all 16 regions and >90% in 12 of the regions). Conversely, MPRAGE-PROMO demonstrated lower performance than even MPnRAGE without motion correction.

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