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Abstract #4168

Robust quantitative diffusion weighted MR on an MR-Linac system

Tim Schakel1, Rob H.N. Tijssen1, Hans M. Hoogduin2, and Marielle E.P. Philippens1

1Radiotherapy, UMC Utrecht, Utrecht, Netherlands, 2Radiology, UMC Utrecht, Utrecht, Netherlands

Quantitative diffusion weighted imaging is demonstrated on a clinical MR-Linac system. ADC values were measured using a standardized diffusion phantom using two different diffusion sequences, single shot EPI and single shot TSE: SPLICE. In general, accurate and repeatable ADC measurements could be acquired using both sequences. EPI showed more susceptibility and eddy current related image distortions, whereas SPLICE was geometrically more robust. Large deviations in ADC start to occur when moving further away from the isocenter, suggesting the need for gradient non-linearity correction of ADC values.

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