132 patients with invasive breast cancer were imaged with our DCE-MRI protocol incorporating ultrafast, DISCO imaging of early wash-in phase with standard, steady state DCE-MRI. Heuristic and pharmacokinetic metrics were calculated from the DISCO and steady state images and compared between invasive lobular and invasive ductal carcinomas. Bolus Arrival Time was significantly higher in ILC than in IDC. Association of parameters with pathological complete response to neoadjuvant chemotherapy administered after the imaging exam was investigated for a subset of 25 patients. Heterogeneity-related parameters were significantly higher in the pCR group encouraging further investigation into imaging biomarkers predictive of treatment response.