Abstract #4535

Analysis of colour discrimination ability in Parkinson’s Disease patients using fMRI

Shefali Chaudhary¹, Senthil Kumaran¹, Vinay Goyal², Achal Srivastava², Gaurishanker Kaloiya³, Mani Kalaivani⁴, Rajesh Sagar⁵, and Naranamangalam R Jagannathan¹

¹Department of NMR and MRI Facility, All India Institute of Medical Sciences, New Delhi, India, ²Department of Neurology, All India Institute of Medical Sciences, New Delhi, India, ³Department of NDDTC and Psychiatry, All India Institute of Medical Sciences, New Delhi, India, ⁴Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India, ⁵Department of Psychiatry, All India Institute of Medical Sciences, New Delhi, India

Ocular and visual disorders has been reported in Parkinson’s Disease (PD). BOLD activation was mapped during visual color hue discrimination stimuli in PD (n=10, mean age=59 years, SD=6.8) and healthy control (HC) (n=6, mean age=53.67 years, SD=2.6) participants at 3 T MR scanner. Comparison between the two groups revealed lower activation in secondary visual areas (BA 18/19) and fusiform gyrus (BA 37), more dependence on memory areas and increased cluster size in PD (in comparison with HC) suggesting impairment in colour hue processing.

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