This retrospective study investigates the possibility of distinguishing between clear cell renal cell carcinoma ( ccRCC ) and non-clear cell renal cell carcinoma ( nccRCC ) using MRI-derived parameters by exploring a predictive method. We enrolled the patients with three common subtypes of renal tumor - clear cell renal cell carcinoma ( ccRCC ), papillary renal cell carcinoma ( pRCC ) and chromophobic renal cell carcinoma ( cRCC ). We combined pRCC and cRCC into one subtype - nccRCC. Our results demonstrated that MRI texture analysis can differentiate ccRCC from nccRCC with high specificity, sensitivity and accuracy and can probably facilitate the precise treatment of renal tumors in the future clinical practice.
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