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Abstract #4633

Differences in BOLD temporal behavior in the cortical and subcortical structures of the visual and somatosensory systems

Daniil P. Aksenov1, Michael J. Miller1, Limin Li1, and Alice M. Wyrwicz1

1NorthShore University HealthSystem, Evanston, IL, United States

The temporal behavior of the BOLD response can vary considerably between nodes within sensory circuits as well as across different modalities. Understanding the nature of these variations could provide more information about the factors that shape the hemodynamic response. In this work fMRI data were acquired from both thalamic and cortical regions of the visual and somatosensory systems during prolonged sensory stimulation. Our findings show that while the thalamic BOLD responses for both circuits were quite similar, the cortical responses showed different adaptive behavior, which may reflect underlying regional differences in the contributions of local excitatory/inhibitory processes.

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