It has been suggested that hippocampal subfields show functional specialization. Resting-state functional MRI studies have improved our understanding of brain function. Using rs-fMRI, we examined the possibility of segmenting the hippocampal subfields at 7T and assessed the functional correlations between the hippocampal subfields with other cortical regions. This method was tested in both healthy controls and temporal lobe epilepsy patients. Only small differences in functional connectivity between healthy controls and epilepsy patients were found. This study demonstrated the potential of assessing the resting-state functional connectivity of the hippocampal subfields with other regions of interest in the cortex.
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