To investigate the relationship between splenic MR elastography (MRE) and esophageal varices (EV). 167 patients underwent endoscopy and abdominal MR examination within 3-months interval were enrolled. MRE was performed with passive driver on right and left chest wall separately. The mean stiffness value of liver and spleen was determined. A good correlation between splenic stiffness and EV, but no correlation for liver stiffness was found. Our results demonstrated that spleen stiffness measured by MRE was significant correlated with EV grading. With 9.77 kPa spleen stiffness might be helpful in predicting presence of EV for patients with chronic liver disease.