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Abstract #4715

Evaluating Response of Locally Advanced Gastric Adenocarcinoma to Neoadjuvant Chemotherapy using Intravoxel Incoherent Motion MRI: A Preliminary study

Yongjian Zhu1, Liming Jiang1, Ying Li1, and Lizhi Xie2

1Department Of Imaging Diagnosis, National Cancer Center / Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China, 2GE healthcare, China, Beijing, China

Intravoxel incoherent motion (IVIM) diffusion-weighted magnetic resonance imaging (DW-MRI) has been applied in research of different cancers, however its potential in gastric cancer has not been fully explored. In this study, we explored the value of IVIM parameters in evaluating the response to chemotherapy in gastric cancer. We found that the D and f values showed good diagnostic performance by differentiating responders from nonresponders, this could provide effective help for the choice of clinical treatment.

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