This study explored the value of MR T1ρ in patients with chronic hepatitis B. Twenty normal control subjects and forty-eight patients with chronic hepatitis B, including twenty-two patients who were confirmed by liver biopsy (F1/F2/F3=8/8/6) took the MR T1ρ scan. T1ρ value showed significant increase in patients with chronic hepatitis B compared with normal control subjects, significant correlation with liver fibrosis staging and higher sensitivity and specificity in identifying F1 to F3 of liver fibrosis. We conclude that MR T1ρ can provide reliable T1ρ values and can be used to assess liver fibrosis.
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