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Abstract #4888

Assessment of Myocardial Fibrosis in Uremic Cardiomyopathy using Cardiac MR Native T1 Mapping: A Comparison with Coronary Artery Calcium Score

Shengjia Gu1 and Wenjie Yang1

1Radiology, Ruijin Hospital, Shanghai, China

Congestive heart failure is the leading cause of death in patients with end-stage renal disease. The process of this type of dysfunction is termed uremic cardiomyopathy. Extensive myocardial fibrosis, which leads the process, has also been shown to be a stronger predictor of death. Recently, anti-fibrosis has risen as a hot target in the treatment of uremic cardiomyopathy. Therefore, its urgent to find a more accurate and non-invasive method in order to meet the demand of clinic.In this study, we use the native T1 mapping to assess the level of myocardial fibrosis in ESRD patients´╝îcomparing with the Coronary Artery Calcium Score, in order to evaluate its accuracy in diagnosis uremic cardiomyopathy.

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