Abstract #5016

Comparison of cardiac output calculated from low dose Ultra-fast DCE MRI to the values measured from cardiac MRI

Shiyang Wang¹, Yue Zhang¹, Xiaobing Fan¹, Dianning He¹, Milica Medved¹, Tatjana Antic², Ambereen Yousuf¹, Gregory Karczmar¹, and Aytekin Oto¹

¹Radiology, University of Chicago, Chicago, IL, United States, ²Pathology, University of Chicago, Chicago, IL, United States

Accurately measuring arterial input function (AIF) is essential for quantitative dynamic contrast enhanced (DCE) MRI. The indicator dilution principle was used to verify the accuracy of AIF measured at iliac arties following injection of low dose (0.015 mmol/kg) gadolinium contrast media. The cardiac output from cardiac MRI (CO_CMRI) were compared with the cardiac output from Ultra-fast DCE-MRI (CO_DCE). Results demonstrated that the CO_DCE were consistent with the ‘gold standard’ CO_CMRI. This demonstrates that the low dose ultra-fast DCE-MRI can be used to accurately measure the AIF.

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