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Abstract #5022

Investigating the nature of distinct regions in brain tissue affected by stroke with principal component analysis of multi-b valued diffusion data

Ana-Maria Oros-Peusquens1, Omid Nikoubashman2, Martin Wiesmann2, and N. Jon Shah1

1Institute of Neuroscience and Medicine 4, Medical Imaging Physics, Research Centre Juelich, Juelich, Germany, 2Department of Neurology, Faculty of Medicine, RWTH Aachen University, Aachen, Germany

A data-driven, observer-independent segmentation of brain regions affected by stroke is proposed. It is based on PCA analysis of a multi b-value diffusion trace acquisition and offers fast, high-SNR visualisation of affected areas. Substructure of these areas is easily identified and can be automatically delineated using clustering algorithms.

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