Multi-shot diffusion-weighted MRI allows for higher spatial resolution than single-shot approaches, but suffers from image artifacts due to motion-induced shot-specific phase variations. Advanced parallel imaging reconstructions can mitigate these effects, but a comparison of these approaches is still missing, especially for the widespread EPI. Following the concept of reproducible research, a number of algorithms were implemented, adapted and refined for EPI, and compared in simulations and in-vivo. Results show different performance and applicability. The iterative feedback and the sharing of joint global information in the reconstruction and appropriate constraints were found to be crucial for high-quality high-resolution DWI.
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