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Abstract #5397

Spinal Cord Perfusion is Associated with Diffusion and clinical mJOA score in Preoperative Patients with Cervical Spondylotic Myelopathy

Chunyao Wang1, Xiao Han2, Wen Jiang2, Guangqi Li1, Jinchao Wang2, Hua Guo1, and Huijun Chen1

1CBIR´╝îschool of medicine, Tsinghua University, Beijing, China, 2Jishuitan hospital, Beijing, China

Cervical Spondylotic Myelopathy (CSM) is a chronic progressive disorder of spinal cord with a relatively ill-defined onset of pathogenesis. A series of state-of-art quantitative and functional MR imaging techniques have been proposed aiming to find out specific indicators in prediction and diagnosis of CSM at early phase, but lack of sufficient evidences. Spinal cord blood supply change was recognized as one of the crucial pathophysiological process in CSM. Hence, we investigate the relationship between spinal cord blood perfusion assessed by MR DSC with DTI metrics and clinical mJOA score. Finally, we find spinal cord blood flow is significantly correlated with diffusion metrics and mJOA.

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