Abstract #5403

Low Apparent Diffusion Coefficient Value Predicts Early Progression of Skull Base Meningiomas

Ching Chung Ko¹, Sher Wei Lim², Tai Yuan Chen¹, Jeon Hor Chen^3,4, Chien Feng Li⁵, and Yow Ling Shiue⁶

¹Medical Imaging, Chi Mei Medical Center, Tainan, Taiwan, ²Neurosurgery, Chi Mei Medical Center, Chiali, Tainan, Taiwan, ³Radiology, E-Da Hospital/I-Shou University, Kaohsiung, Taiwan, ⁴Center for Functional Onco-Imaging, University of California Irvine, Irvine, CA, United States, ⁵Pathology, Chi Mei Medical Center, Tainan, Taiwan, ⁶Institute of Biomedical Science, National Sun Yat-Sen University, Kaohsiung, Taiwan

A recent study described the extent of tumor resection and ADC values could offer better prediction of progression/recurrence (P/R) in meningiomas than histopathological grading. Although complete resection of tumor is a key determining factor of recurrence in meningiomas, it is often difficulty to achieve for the skull base meningiomas (SBM) due to complex neurovascular structures. In this study, we investigated the preoperative CT and MR imaging features for the prediction of early P/R in SBM, with emphasis on ADC values. Our results found that low ADC value and adjacent bone invasion could predict high risk of early P/R in SBM, and therefore, offer clinically vital information for the planning of treatment.

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