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Abstract #5532

3D MRI of Blood Flow of Human Retina

Xiang He1, Kenneth T Wengler2, Andrew LaBella2, Tao Wang1, Patricia Stefancin1, and Tim Q Duong1

1Radiology, Stony Brook University Hospital, Stony Brook, NY, United States, 2Biomedical Engineering, Stony Brook University, Stony Brook, NY, United States

Previous studies have shown that blood flow in the human retina can be measured using MRI. These studies used single-slice 2D pseudo-continuous arterial spin labeling (pCASL) which has limited spatial coverage and resolution, and is susceptible to through-plane eye motion. In this study, a pCASL with zoom-3D TSE VFA acquisition was developed to provide whole-eye coverage with 0.5×0.5×4mm3 resolution and reduced motion induced image blur. This approach should prove useful for studying different retinal disorders such as glaucoma, diabetic retinopathy and retinal ischemia.

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