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Abstract #5602

Real-time ECG-gated continuous vibration multi-shot spiral elastography acquisition: application to time-resolved cerebral stiffness measurements during arterial pulsation.

Carsten Warmuth1,2, Felix Schrank1, Thomas Elgeti1, Jürgen Braun3, and Ingolf Sack1

1Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany, 2Visage Imaging GmbH, Berlin, Germany, 3Institute for Medical Informatics, Charité - Universitätsmedizin Berlin, Berlin, Germany

We implemented a versatile spiral MRE sequence that synchronizes the acquisition in real-time to a continuous harmonic vibration. Using multi-shot gradient echo readout and fractional motion encoding, multiple phases can be acquired in the cardiac cycle with high temporal resolution. Optionally, prospective respiratory gating and slice tracking allow for imaging moving organs like the heart or the liver in free breathing. As a first application, we measured cerebral stiffness maps in multiple phases of the cardiac cycle to detect changes induced by arterial pulsation.

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