MRI has become the mainstay for noninvasive fat quantification in liver in routine clinical practice. To quantify fat fraction, the Dixon method is used most often. However, it is associated with a nontrivial image reconstruction process. In this study, we aim to perform fat quantification using the slice-selective gradient reversal (SSGR) technique, which was proposed previously but has not been validated in human liver. Our evaluation shows that the technique can efficiently separate water and fat, quantifying fat fraction that is highly correlated with that using the Dixon method.