This work investigates the accuracy and precision of T2∗ estimated from standard water–fat imaging techniques with respect to the a priori assumed fat spectrum. A bias in measuring T2∗ with a low number of echoes and a mismatch of the a priori to the true fat spectrum is detected. Through simulations and in vivo scans it is shown how the bias is reduced by increasing the number of echoes. Results also indicate remaining inaccuracies due to a mismatch in the assumed fat spectrum to the true fat spectrum in a voxel.
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