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Abstract #5619

Simultaneous T1/T2 Mapping of Hyperpolarized 13C Compounds using the bSSFP Sequence

Eugene Milshteyn1, Galen D. Reed2, Jeremy W. Gordon1, Peng Cao1, Cornelius von Morze1, Shuyu Tang1, Andrew Leynes1, Peder E. Z. Larson1, and Daniel B. Vigneron1

1Radiology and Biomedical Imaging, UCSF, San Francisco, CA, United States, 2GE Healthcare, Dallas, TX, United States

Hyperpolarized 13C imaging development has enabled monitoring of different physiological processes, such as metabolism and perfusion, in various diseases, such as cancer and diabetes. The relaxation parameters T1 and T2 are essential in sequence optimization and modeling, and can be used for assessment of healthy versus diseased tissue. The goal of this project was to develop and apply simultaneous in vivo T1 and T2 mapping of hyperpolarized 13C probes using bSSFP sequence. Results indicated multiple approaches can be used to obtain high resolution T1 and T2 maps.

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