STimulated Echo based Mapping (STEM) of T1, T2 and Apparent Diffusion Coefficient
Yuxin Zhang1,2, Xiaoke Wang1,3, Valentina Taviani4, and Diego Hernando1,2
1Radiology, University of Wisconsin Madison, Madison, WI, United States, 2Medical Physics, University of Wisconsin Madison, Madison, WI, United States, 3Biomedical Engineering, University of Wisconsin Madison, Madison, WI, United States, 4Global MR Applications & Workflow, GE Healthcare, Menlo Park, CA, United States
This study proposed an approach for joint estimation of T1 and T2 relaxation as well as quantitative diffusion parameters. The proposed approach has been evaluated in quantitative relaxation-diffusion phantom, in-vivo brain imaging and prostate imaging. The overall T1, T2 and ADC measurements have been shown to be accurate compared to reference maps. In this feasibility study, the acquisition was over-sampled in TM-TE-b space, which limited the scan time. Future work will introduce undersampling and protocol optimization. In summary, this method has the potential to enable multi-dimensional tissue characterization in clinically feasible acquisition times.
This abstract and the presentation materials are available to members only;
a login is required.