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Abstract #5646

An investigation into the effect of body composition on the agreement between whole-body fat mass determined by MRI and air-displacement plethysmography.

Andrew Weedall1, Adrian Wilson2,3, and Sarah Wayte1

1Department of Clinical Physics and Bioengineering, University Hospitals Coventry and Warwickshire, Coventry, United Kingdom, 2Research and Development Department, University Hospitals Coventry and Warwickshire, Coventry, United Kingdom, 3Department of Physics, University of Warwick, Coventry, United Kingdom

The agreement between whole-body fat mass determined using MRI and air-displacement plethysmography (ADP) was investigated for a range of non-pathological body mass indexes (BMIs). The whole-body fat mass was determined for ten volunteers by two methods: firstly by ADP using a BODPOD®; and secondly using two different MRI sequences (LAVA-flex and IDEAL IQ). The whole-body fat mass determined by both MRI protocols showed good agreement with, but were consistently higher than, the ADP determination (mean difference: LAVA-flex=4±3kg; IDEAL IQ=2±3kg). In addition, analysis of Bland-Altman plots showed no change in the differences between the MRI and ADP fat mass with BMI.

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