Neurodegenerative diseases are a large group of conditions with progressive, but variable, neurological deterioration over time. Dementia is a hallmark in many of these diseases. Classification using clinical phenotypes is suboptimal due to broad overlap in clinical manifestations, and recent approaches have favoured using neuropathological and biochemical criteria instead.
Neuroimaging using magnetic resonance imaging (MRI) has good correlation with the neuropathological classification, and can be used to aid the clinician in making an accurate diagnosis. This education exhibit provides an MRI pictorial review of the neurodegenerative diseases which are more common, and/or are more clearly defined from a neuropathological standpoint.