This study evaluated q-space-based (genSD) and principal component analysis (PCA) denoising techniques to enhance SNR for peripheral nerve diffusion MRI of 10 healthy knees. The combination of both methods (PCA+genSD) was compared with a PCA-only method as well as the average of 10 repetitions. The combined denoising method showed improved performance with respect to SNR, peripheral nerve conspicuity and reproducibility.
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