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Abstract #0263

Efficient Dictionary-based Attenuation Correction for combined PET-MR systems

Matteo Cencini1,2, Guido Buonincontri2, and Michela Tosetti2,3

1Department of Physics, University of Pisa, Pisa, Italy, 2IMAGO7 Foundation, Pisa, Italy, 3IRCCS Stella Maris, Pisa, Italy

In many diagnostic applications, a correct photon attenuation correction is crucial for quantifying the uptake of a PET tracer. While in PET/CT scanners attenuation map is readily estimated from CT Hounsfield units, in combined PET/MRI scanners it must be obtained by processing of high resolution images. This map must then be co-registered to low resolution PET map, wasting acquisition time. Here, we propose an efficient approach based on a fast transient-state acquisition and a three-component signal model: this allow to obtain tissue fraction maps, which can be used to estimate attenuation map, directly at PET resolution.

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