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Abstract #0310

Echo Planar Time-Resolved Imaging (EPTI) with subspace constraint and optimized k-t trajectory

Zijing Dong1,2, Fuyixue Wang1,3, Timothy G. Reese1, Berkin Bilgic1, and Kawin Setsompop1,3

1A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 2Electrical Engineering and Computer Science, MIT, Cambridge, MA, United States, 3Harvard-MIT Health Sciences and Technology, MIT, Cambridge, MA, United States

Echo planar time-resolved imaging (EPTI) is a multi-contrast quantitative imaging technique, which achieved fast acquisition of distortion- and blurring-free images at multiple echo times (TE). To improve the SNR and accuracy of EPTI at high-accelerations, in this study, we developed a subspace-constrained reconstruction for EPTI and proposed new k-t sampling trajectories to take advantage of this reconstruction. The subspace reconstruction is also augmented with phase-cycling to extract high-resolution phase data, without need of high-resolution B0 calibration scan. Using the proposed approach, whole-brain 1.1mm-isotropic multi-echo images, and T2* and B0 maps are reconstructed from 3D-EPTI data acquired within 50 seconds.

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