Purpose: To study comparatively and longitudinally the connectome changes from childhood (age 10 years) to adolescence (age 15 years) using white matter fibrography (WMF). Methods: WMF was used to generate the connectomes of 9 extremely preterm born individuals using MRIs obtained at ages 10 and 15 years. Results: The most noticeable connectome change was a marked increase in the fiber density accompanied by fiber thinning. Conclusion: As anticipated, WMF connectomics of the extremely preterm brain demonstrate clearly observable WM architectural changes from 10 to 15 years of age from sparse fiber-thick to dense fiber-thin.
This abstract and the presentation materials are available to members only; a login is required.