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Abstract #0535

Characterization of BOLD hemodynamic response function in subcortical and cortical regions of human brain at 3T and 9.4T

Jung Hwan Kim1, Amanda Taylor1, Marc Himmelbach2, Gisela Hagberg2,3, Klaus Scheffler2,3, and David Ress1

1Baylor College of Medicine, Houston, TX, United States, 2University of Tuebingen, Tuebingen, Germany, 3Max Planck Institute for Biological Cybernetics, Tubingen, Germany

Measurement of blood oxygen level dependent hemodynamic response function (BOLD HRF) can be used to evaluate neurovascular coupling and understand underlying physiology (e.g. oxygen uptake and blood flow). However, there is dearth of understanding subcortical neurovascular coupling, which is critical for brain health. Here, we characterize human subcortical HRFs at both 3T and 9.4T and compare them with HRFs in visual cortex.

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