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Abstract #0644

Magnetic Resonance Fingerprinting of the Normal Pancreas

Joshua Kaggie1,2, Eva Mendes Serrao1,2,3, Dimitri A Kessler1,2, Mary McLean3, Bruno Carmo1,2, Guido Buonincontri4, Rolf F Schulte5, Evis Sala2,3, Kevin M Brindle3, Amy Frary1,2, Martin J Graves1,6, and Ferdia Gallagher2,3,7

1Radiology, University of Cambridge, Cambridge, United Kingdom, 2Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom, 3Cancer Research UK, Cambridge, United Kingdom, 4IMAGO7 Foundation, Pisa, Italy, 5GE Healthcare, Munich, Germany, 6Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom, 7University of Cambridge, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom

MR imaging of the pancreas is challenging due to its retroperitoneal deep-sited location in the abdomen. In addition to its position, the pancreas is subject to breathing motion artifact, which limits the clinical value of pancreatic MRI. Patients with pancreatic cancer are usually very frail, which limits their tolerance to long examinations or breath-hold MRI measurements. MR Fingerprinting (MRF) is an innovative measurement technique that provides qualitative data and quantitative parameter maps from a single acquisition with the potential to reduce exam times. MRF is technically challenging due to limitations in processing capabilities, which we assess in this work.

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