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Abstract #0743

Comparison of Four 3D Black Blood MRI Sequences for the Characterization of Unruptured Intracranial Aneurysm Wall Enhancement

Chengcheng Zhu1, Bing Tian2, Laura Eisenmenger1, Qi Liu2, Jianping Lu2, Christopher Hess1, and David Saloner1

1Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States, 2Radiology, Changhai Hospital, Shanghai, China

Aneurysm wall enhancement (AWE) post Gadolinium contrast on high-resolution black blood MRI has been studied as a marker of unstable intracranial aneurysms. However, a recent study showed slow flow could mimic AWE. This study evaluated four black blood sequences with high- and low-resolution fast-spin-echo (SPACE), with and without MSDE/DANTE blood suppression modules. In 30 unruptured saccular aneurysms, we found low-resolution SPACE significantly overestimated AWE (20/30 enhanced) compared to high-resolution SPACE (16 enhanced) and sequences with MSDE/DANTE (14 and 13 enhanced). High-resolution DANTE-SPACE has the best blood suppression and image quality, which is a preferred method for AWE assessment.

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