Tissue stiffness is a known marker of malignancy and has been shown to change due to thermal therapies. A shear wave elastography technique compatible with magnetic resonance guided focused ultrasound technology is demonstrated in a cadaver breast specimen. Volumetric shear wave speed maps acquired using a multiple-point sonication pattern before and after an MRgFUS ablation demonstrate that a change in shear wave speed can be detected. This technique provides a functional stiffness metric that is complementary to currently used monitoring and assessment techniques in MRgFUS treatments.
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