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Abstract #0817

Rapid open source prototyping of Magnetic Resonance Fingerprinting using Pulseq to enable multi-site two vendor studies

Enlin Qian1, Sairam Geethanath1, Jon-Fredrik Nielsen2, and John Thomas Vaughan Jr1

1Columbia University MR research center, Columbia University, New York, NY, United States, 2Functional MRI Laboratory, University of Michigan, Ann Arbor, MI, United States

This work develops an open source package that allows for rapid prototyping of magnetic resonance fingerprinting (MRF) using Pulseq. In this work, an inversion recovery steady state free precession (IR-SSFP) sequence is designed in Pulseq. TR, flip angles, and TE are selected to achieve variations of contrast. The sequence was implemented, simulated, and applied on five health volunteer brain scans. The scan time of one subject for single slice sequence was 35 seconds. The data was sliding window reconstructed and matched with the simulated dictionary. The dictionary matching shows similar T1 and T2 results as reported in literature.

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