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Abstract #0858

Hemispheric Specification of Remote Effect of Cerebral Glioma on White Matter Connectivity

Siqi Cai1, Chunxiang Jiang1,2, Xiaojing Long1, Zhifeng Shi3, Liang Chen3, Kai Wang4, Hairong Zheng1, Xin Liu1, and Lijuan Zhang1

1Shenzhen Institutes of Advanced Technology,Chinese Academy of Sciences, Shenzhen, China, 2University of Chinese Academy of Sciences, Beijing, China, 3Department of Neurosurgery, Huashan Hospital of Fudan Univesity, Shanghai, China, 4Beijing Tian Tan hospital,Capital Medical University, Beijing, China

Biological aggressiveness of glioma extends beyond the radiological territory. Based on the atlas based method and diffusion metrics derived from diffusion tensor imaging, the remote effect of cerebral gliomas on the white matter connectivity was analyzed at the global level. LGGs and HGGs showed difference in the diffusion metrics in the contralesional brain regions with hemispheric and anatomical specifications, which possibly underlie the functional neuroplasticity confounding the aggressiveness assessment and management of glioma.

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