Parkinson’s disease (PD) is one of the most common neurodegenerative disorder in the aging population1, characterized by progressive deterioration of motor function as well as non-motor symptoms2,3. To date, most of the resting-state fMRI PD studies focused on basal ganglia3,4,5, whereas few studies on cerebellum5,6, especially cerebellar vermis. In this study, we investigated the rs-FC difference in whole brain in PD patients compared with health controls and the association between FC of vermis and motor and neuropsychological measurements in PDs. Our results suggest that the cerebral vermis, visual cortex, and visual processing associated areas contribute to the development of symptoms in PD.
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