The purpose of this study was to demonstrate the feasibility of a novel method for precise radiologic-pathologic correlation of liver metastases, in patients undergoing curative resection. Intraoperative gadoxetic acid was administered to patients at the time of partial hepatectomy prior to vascular inflow ligation. Ex vivo MRI was then performed using an MR-compatible sectioning device to identify lesion coordinates to inform pathologic processing. Results from resection specimens in 6 patients with a total of 25 liver lesions are presented. The study’s novel radiologic-pathologic correlation method combines intraoperative gadoxetic acid administration and ex vivo MR imaging to perform accurate lesion localization.