This study aim to combine multimodal MRI with liver volume for quantitative assessment of liver function in patients with cirrhosis. Eighty-five subjects underwent GD-EOB-DTPA enhanced MR and IVIM-DWI.Through statistical analysis, RE, D* and Vliver/Vspleen from modeling group were selected as optimal indicators. Using multiple regression to establish a multi-parametric model for liver function assessing: F(x). The ROC analysis of the validation group showed that it had an AUC of 0.973 in distinguishing Child-Pugh A group and Child-Pugh B and C group. The results showed it could evaluate the overall liver function and expected to be a method for preoperative local liver function assessment.